WHAT DOES IT ACTUALLY MEAN: DEEP TISSUE MASSAGE? AND IS IT IMPORTANT? YES! (health project99+)

Uganda, mother and son

Dear reader,

Does one always understand what one reads? In my case I often don’t. Take for example “deep tissue massage”. Highly recommended by any masseur. But why? What does it mean? What tissue she (my masseur) is talking about? Apparently about connective tissue. What is this? And what about the muscles? 

Household words in this context are collagen, cartilage, osteoarthritis. In the world of connective tissue there is a lot of hype, exaggeration and fake promises. So be careful and do not fall for all the claims. The good news is that studies show that massage has positive effects on your tissues. Massage also benefits your overall health as it is integral to your immune system; in particular the deep tissue massage.

1.Introduction

We all know that muscle loss, or sarcopenia, is something we should prevent. Without action, an average woman can lose approximately 6 kg of muscle between the ages of 25 and 65. It is also important to keep flexibility. Strength and resistance training, tai chi, and yoga are all beneficial activities. They are effective and also enjoyable. These activities support overall health.

Massage should be included in this list of active health interventions, both for prevention and treatment. Many of us tend to visit a masseur only when we face problems. Still, regular massages can help keep the body loose and flexible, contributing significantly to overall health. This blog will explore this topic further.

A central choice offered by massage therapists is the so-called deep tissue massage. Contrary to what some might think, deep tissue massage is not just about treating superficial muscles beneath the skin. It primarily targets deeper layers of both muscle and connective tissue. The main goal is to relieve tension in muscles that are chronically tight. These contracted muscles can detrimentally affect your health more than you might realize. Consider it a two-step approach: addressing issues in the connective tissue to effectively reach the deeper layers of muscle.

I strongly encourage readers to educate themselves about different types of massage techniques. This knowledge can help you determine how to best incorporate massage into your health routine.

2. To start, what exactly is “connective tissue”?

Humans have four main types of tissues. Connective tissues are the focus of this blog. Epithelial tissues are also important (see note at the bottom of this blog). In addition, there are muscle and nervous tissues.

Connective tissue is essential for maintaining the body’s structural integrity. It facilitates communication and transport. It provides protection and supports various physiological functions. It is a vital component of the overall body system.

Connective tissue is composed of a variety of cells (see note at the bottom of this blog). It also includes fibers and an extracellular matrix (see note at the bottom of this blog). The composition and structure of the extracellular matrix can vary widely among different types of connective tissue. These include loose connective tissue, dense connective tissue, cartilage, bone, blood, and adipose (fat) tissue.

3. What different types of connective tissue are there?

  • Loose Connective Tissue. (Provides support and elasticity; found beneath the skin and surrounding organs).
  • Dense Connective Tissue. (Composed of closely packed collagen fibers and provides tensile strength; found in tendons and ligaments).
  • Adipose Tissue. (Specialized fat storage for insulation and energy storage).
  • Cartilage. (Provides flexible support; found in joints, the nose, and ears).
  • Bone. (Provides structural support and protection; stores calcium and produces blood cells). 
  • Blood. (A liquid connective tissue responsible for transport and communication within the body) 
  • Lymph. (Part of the immune and circulatory systems; helps transport lymphatic.

4. And what are the many functions of connective tissue?

In short, it provides structural support and shape to the body. 

In line with this, connective tissue plays a crucial role in anchoring and binding other tissues and organs together. Tendons connect muscles to bones. Ligaments connect bones to other bones at joints. Both tendons and ligaments are types of connective tissue.

Blood is a specialized type of connective tissue responsible for transporting nutrients, gases, hormones, and waste products throughout the body. 

An important function of some connective tissues is the protection of organs. For instance, adipose tissue (fat) acts as a cushion, providing protection for vital organs.

Moreover, connective tissue is integral to the immune system. It houses various cells involved in immune responses, such as macrophages and lymphocytes. These cells help defend against pathogens (substances that can cause illness). It also stores energy and nutrients. Adipose tissue stores fat for energy reserves. Bone tissue stores essential minerals like calcium and phosphorus.

Another well-known function of connective tissue is seen in cartilage. It provides flexibility and support in joints. This allows for smooth movement without friction between bones.

Additionally, connective tissue plays a vital role in the healing and repair of tissues after injury. It can regenerate and form scar tissue to restore structure and function. Connective tissue also contains signaling molecules and fibers that facilitate communication between different cells and tissues in the body.

5. The relationship between connective tissue and aging is multifaceted

Age-related changes can lead to decreased strength, elasticity, and overall resilience of connective tissues. While it is not possible to completely stop the effects of aging on connective tissue, there are several strategies. These strategies may help slow the process and mitigate the negative impacts. Aging is a natural biological process, and connective tissues, like all tissues in the body, undergo changes over time. 

Maintaining a healthy lifestyle that includes regular exercise, a balanced diet rich in nutrients that support connective tissue health (like vitamin C, omega-3 fatty acids, and amino acids/protein), staying hydrated (drink a lot during the day!), and avoiding smoking can help mitigate some of the negative effects of aging on connective tissue. 

Protect from Injury. Be mindful of body mechanics and use protective gear during activities that risk injury. Avoid repetitive strain and take breaks to prevent overuse injuries.

Some people may find benefits from supplements that support joint health, such as glucosamine, chondroitin, collagen peptides, or hyaluronic acid. I already wrote about glucosamine and will write about a LED mask. Interesting things going on. 

6. Well known issues with your tissues……

  • Reduced Collagen Production. Collagen is the primary protein in connective tissue, providing structure and strength. As we age, the body’s ability to produce collagen decreases. This causes a decrease in the elasticity and firmness of skin, contributing to wrinkles. It also leads to increased joint stiffness. Additionally, there is a higher risk of injuries. How to compensate this collagen loss is a billion-dollar business, with only few products and methods that work. I write about in another blog.
  • Elastin Degradation. Elastin fibers allow tissues to resume their shape after stretching. Aging can lead to the breakdown of elastin. This can result in less elastic skin and blood vessels, leading to sagging skin and potential cardiovascular problems.
  • Changes in Ground Substance. Aging can reduce the moisture content in connective tissue. This reduction leads to stiffness in the body. It also results in decreased cushioning in joints (osteoarthritis). This is the result of changes in certain glycans that help keep moisture and offer resilience to tissues.
  • Increased Cross-Linking. where sugar molecules bond with proteins. The age-related misery does not stop. Cross-linking can lead to decreased flexibility and increased rigidity in tissues. This contributes to conditions like reduced mobility and joint pain.
  • Degenerative Changes leading to osteoarthritis. Connective tissues can undergo degenerative changes, including the wear and tear of cartilage in joints. This can lead to osteoarthritis, characterized by pain, stiffness, and reduced mobility.
  • Increased Risk of Injuries. As connective tissues become less resilient and more rigid with age, they are more susceptible to strains, sprains, and tears. Older adults may experience more frequent injuries and longer recovery times.
  • Inflammatory Changes. Aging is also associated with a low-grade inflammatory state, which can affect connective tissues and their healing processes. Chronic inflammation can exacerbate the degeneration of connective tissues and contribute to age-related diseases.
  • Impact on Healing: The capacity for connective tissue repair tends to decline with age. This means injuries may take longer to heal.
  • 7. Main effects of deep tissue massage on connective tissue
  • Deep tissue massage can positively affect connective tissue health. It does so through mechanisms like (1) fibroblast stimulation and (2) inflammation reduction. It also includes (3) collagen remodeling and (4) enhanced hydration. 
  • (1). Fibroblast Activity. Fibroblasts are cells responsible for producing collagen. They also produce other components of the extracellular matrix. These are crucial for maintaining the integrity of connective tissue.  Studies suggest that massage can stimulate fibroblast activity, potentially enhancing collagen production, which helps improve tissue elasticity and strength.
  • (2). Inflammation Reduction. Deep tissue massage has been shown to reduce markers of inflammation in the body. This can be beneficial for connective tissue, as chronic inflammation is linked to tissue degeneration and aging. Lowering inflammation can lead to improved healing and recovery from exercise or injury.
  • (3). Collagen Remodeling. Massage can promote collagen remodeling by altering the structure of collagen fibers. This is important for maintaining flexible and functional connective tissue. Manipulative techniques help break down adhesions or scar tissue, enabling better movement and operation of tissues.
  • (4). Tissue Hydration. Massage increases blood circulation, promoting better hydration and nutrient delivery to tissues. Improved hydration is essential for the health of connective tissues, as they need adequate moisture for flexibility and operation.

8.Scientific Studies on frequency and effectiveness

The good news is that research suggests that regular massage can have accumulative benefits. Best seem to be regular sessions. Some studies indeed show that deep tissue massage can be effective in managing chronic pain. It can also help alleviate muscle tension and even reduce stress levels.

9.My experience

  • I could not do without. No more knobs on my back and my whole body feels much better. I support this with exercises and some massage equipment at home.

10. Visualizing connective tissue (for example on your back) can be done through a few different techniques.

You can palpate (gently press) different areas of your back to feel for various structures. You may feel tendons and ligaments that are part of the connective tissue system. It will help if you understand the different muscles of course. Look for diagrams or models (websites, apps) that illustrate the back’s connective tissue structures. There are various apps available that allow you to explore 3D models of human anatomy.

MRI is an imaging technique providing detailed images of soft tissues, including connective tissue, muscles, and fascia. And we have ultrasound as well. This can also be used to visualize soft tissues. It can provide insights into the condition of connective tissues like tendons and ligaments.

Engaging in practices such as yoga or Pilates can enhance your awareness of how connective tissue supports movement. Pay attention to how your body feels during these practices. Notice how it behaves. This can provide indirect insight into the state of your connective tissue.

Understanding the connective tissues in your back requires combining knowledge of anatomy. It involves utilizing technology and imaging. Engaging in physical exploration through touch and movement is also essential.

11. If you have developed knobs or lumps in your back, they might be associated with connective tissue. This condition could be due to various causes. 

Knobs in your back related to connective tissue can stem from a variety of conditions. Some can be prevented and/or solved by physical activity, proper posture, and stress management.

Trigger Points These are small, tight areas within a muscle that can feel like knots. They are often caused by muscle overuse, stress, or poor posture. 

Fascia is a layer of connective tissue that surrounds muscles and organs. Sometimes, due to injury or inflammation, the fascia can develop adhesions or thickened areas that feel like knobs. A masseur can do wonders.

Something similar are lipomas These are benign (non-cancerous) tumors made up of adipose (fat) tissue. They can occur in the subcutaneous tissue, which is just beneath the skin. Lipomas are typically soft and movable and can vary in size. Only a surgeon can remove them. The same applies to fibromas, benign tumors. They can be firm and may or may not cause discomfort.

A strain or tear in a muscle can lead to localized swelling and may form palpable knots. Symptoms may include pain, swelling, and reduced range of motion. Here we have potential work for a masseur and own massage work as well.

Skeletal Conditions like osteophytes, bone spurs that can form on the vertebrae due to degenerative conditions like arthritis. No work for a masseur.

Cysts. Sometimes fluid-filled sacs can develop in areas of connective tissue, leading to a hard or soft lump. They can be painless or cause discomfort.

Conditions like abscesses, infections, or inflammatory disorders can cause localized swelling. Knobby structures may form due to the body’s immune response.

12. When to Seek Medical Attention

If the knobs are new, painful, or growing, consult a healthcare professional for a thorough evaluation. See a professional if they are accompanied by other unusual symptoms, like fever, weight loss, or persistent discomfort.  

13. Some notes

a. Extracellular matrix is a complex network of proteins and carbohydrates. It is found outside of cells. It provides structural support and regulates various cellular functions. There is collagen (provides strength), elastin (provides elasticity), and reticular fibers (provide support. There is also ground substance, a gel-like material that helps hold cells and fibers together; it contains water, proteoglycans, and glycoproteins.

b. Epithelial tissue is a type of tissue that forms protective coverings on body surfaces. It lines cavities and organs. It is also involved in absorption, secretion, and sensation.

c. Various types of cells are found in connective tissue

  • Fibroblasts.Responsible for producing fibers and the ground substance.
  • Macrophages.Involved in immune responses and cleaning up debris.
  • Adipocytes. Store fat and serve as energy reserves.
  • Mast Cells. Play a role in allergic responses and inflammation.
  • Lymphocytes. A type of white blood cell involved in immune response.

Dear readers, this was much too long. There was too much to tell about connective tissue and deep tissue massage so I do not apologise .

Take care and life a long and healthy life.

Robert, your health friend,

5. TRYING TO UNDERSTAND METABOLISM AND METABOLIC HEALTH (health project99+)

Inside a mosque in Samarkand/Uzbekistan

Dear reader,

Metabolism/metabolic health is a concept that all health experts use, but that few people really understand. Neither did I: all I knew wat that it was something to do “with food intake and energy”. And that good metabolism is important . 

1.Looking at metabolism from a disorder/disease point of view

I started to understand metabolism better when I looked at it from a disease point of view. Which diseases are caused by bad metabolism, and which have other causes? It turns out that most diseases are not related to metabolism but occur because of (for example) viruses. In the last para of this blog, I provide an overview of all non-metabolic disorders and diseases. It’s incredible how many diseases there are, by the way .

You can roughly divide metabolic diseases into two groups when we concentrate on them. There are plenty of these diseases as well. One group of disorders or diseases occurs wholly or partly because of your lifestyle. The second group is genetic and inherited. In the second group, you will find many rare diseases. The good news is that developments are progressing quickly. More and more diseases can be cured.

2.Definition of metabolism

After this “disease-focused” introduction, let us turn to the definition of metabolism. 

Metabolism refers to how your body converts food and drink into energy to keep you alive and functioning. Your body’s metabolism never stops — even when you’re resting or sleeping. It constantly sustains basic bodily functions. It involves all the chemical processes occurring in the cells of your body every moment of the day. These processes help you breathe, move, grow, and repair cells, manage hormone levels, regulate body temperature, and much more. If there are no issues, your metabolism is functioning well; if not, you may have a metabolic disorder. 

Metabolism consists of thousands of chemical processes within your cells that keep your body operating effectively. Your metabolism is healthy when all these processes work efficiently. However, if one or more processes do not function properly, you may experience metabolic problems. Consider this analogy: metabolism is like a car, and the various processes are its components. The car operates smoothly when all parts function well.

3.Indicators of a well-functioning metabolic function

A well-functioning metabolism is related to several factors.

  • Energy Production. A healthy metabolism efficiently converts carbohydrates, fats, and proteins from food into usable energy (ATP) while minimizing waste.
  • Nutrient Utilization. A functioning metabolism enables the body to effectively use nutrients. It also allows the body to store nutrients for various bodily functions. These functions include growth, repair, and everyday activities.
  • Metabolism plays a crucial role in weight management. A balanced metabolic rate helps maintain an appropriate weight relative to caloric intake and expenditure.
  • Metabolic health is closely linked to hormone function (e.g., insulin, thyroid hormones), which regulates how the body stores and uses energy.
  • Overall Health. A well-functioning metabolism supports many physiological processes. These include digestion, immune function, and energy levels. It contributes to overall health and well-being.

4.And what is metabolic rate?

Metabolic rate is the rate at which the body converts food into energy through biochemical processes. It reflects how quickly the body burns calories to support essential functions like breathing, circulation, and cell production. It also supports physical activity. 

Metabolism isn’t always functioning at the same “rate.”; this depends per situation and per person. Your body can use more or less energy during different times of the day and for various reasons. The metabolic rate can be influenced by factors such as age, sex, body composition, and levels of physical activity. 

Another term often used is the basal metabolic rate (BMR), which is the energy expenditure at rest. Your basal metabolic rate (BMR) indicates the number of calories your body needs to function at a basic level. Just as with the general metabolic rate several factors can influence your BMR, and the rate is different for everyone. 

Someone with a fast metabolism or fast basal metabolic rate (BMR) burns a lot of calories even while at rest. If you have a slow metabolism or slow BMR, your body needs fewer calories to keep it going. Your metabolic rate alone doesn’t determine your body size, and vice versa.

5.The two main groups of metabolic processes (catabolism and anabolism)

Catabolism is the breakdown of macronutrients (carbs, protein and fats) you consume into their simpler forms. For example, your body breaks down carbohydrates into glucose, which enters your blood as blood glucose (=sugar). These macronutrients are the basis of the fuel your body uses for all its cells.

Anabolism is the opposite of catabolism. Your body takes smaller units (like amino acids)  and puts them together to create bigger structures (like proteins). Anabolism is essential when you get an injury, and your body has to heal. It’s also essential for bone growth and building muscles.

6.How does metabolism affect weight?

Many people believe that metabolic problems are responsible for weight gain or loss. However, your metabolism naturally regulates itself. It meets your body’s specific needs. It is rarely the sole cause of weight fluctuations. In general, if your body uses more calories than you take in, you will lose weight (and vice versa). Nonetheless, several other factors affect how many calories your body requires—many of which are difficult to predict.

The commonly referenced figure of 2,000 calories for daily caloric needs is a very rough guideline. Individual requirements can vary widely based on factors such as age and gender. Activity level and overall health also play a significant role.

In summary, while metabolism is an important factor, it reflects how well your body functions. It measures energy production, nutrient utilization, and maintaining vital physiological processes. Additionally, lifestyle components such as diet, exercise, sleep, and stress significantly influence metabolic function. This underscores the importance of making healthy lifestyle choices to support metabolic health.

7.You often read about homeostasis as well? What is this?

Homeostasis is the process by which living organisms regulate and maintain a stable internal environment despite external changes. This includes the regulation of factors such as temperature, pH, and concentration of ions, ensuring optimal conditions for cellular functions.

8.What are metabolic disorders/diseases?

A metabolic disorder is a condition that arises from issues in processing energy. Your body may not process nutrients properly to function well. Metabolism involves a complex series of biochemical processes. Many different things can go wrong in these processes. This can lead to a wide range of metabolic disorders.

Metabolic processes are complex. Metabolic disorders can present with a wide range of symptoms. These symptoms vary significantly depending on the specific disorder and the individual.

9.There are two main groups of metabolic disorders

Metabolic disorders can be broadly categorized into two main groups: genetic (Inherited) metabolic disorders and acquired metabolic disorders. 

The genetic disorders are conditions that you are born with. They occur due to gene mutations. These mutations affect the metabolism of certain substances in the body.  Many of these types of metabolic disorders are endocrine system conditions and involve hormone imbalances. 

Acquired metabolic disorders are conditions that develop later in life. They are often (but not always) linked to factors such as lifestyle choices, diet, and other health conditions. Examples include type 2 diabetes, metabolic syndrome, and obesity. 

Some acquired metabolic disorders may arise due to other medical conditions, hormonal changes, or environmental factors. Additionally, they can result from damaged or diseased organs or autoimmune attacks on the body’s tissues. For instance, excessive alcohol consumption can lead to liver damage. This damage can result in metabolic dysfunctions related to the liver. One example is alcoholic liver disease.

10.Lifestyle: which factors are in your control?

Genetic and age-related factors significantly impact metabolic rate. Nonetheless, individuals can actively manage their lifestyle choices. This management can influence their overall metabolic health. Hence, it’s oversimplified to say that metabolism and metabolic rate are mostly out of one’s control.

  • Eat balanced meals regularly. Don’t skip meals. Your metabolism works best when it has a steady source of energy. Skipping meals or eating too few calories can slow down your metabolism.
  • Focus on nutritious foods. Choose fresh fruits and vegetables, lean proteins, whole grains and healthy fats.
  • Stay active. Exercise, especially strength training and resistance exercises, helps build muscle. Muscle burns more calories than fat, even at rest. This can boost your metabolic rate.
  • Get enough sleep. Quality sleep is essential for a healthy metabolism. Lack of sleep can disrupt your hormones and slow down your body’s ability to use energy efficiently.
  • Stay hydrated. Drinking enough water helps your body’s metabolic processes work properly. Even mild dehydration can slow down your metabolism.
  • Avoid extreme diets or long-term fasting. Drastic calorie cuts or prolonged fasting can slow your metabolism and cause your body to store energy.
  • Avoid stress.

11.Which factors are outside your control?

  • Your genetic makeup can influence your metabolic rate and how your body processes energy.
  • Metabolism typically slows down with age due to loss of muscle mass and hormonal changes.
  • Men generally have a higher metabolic rate than women, primarily due to higher muscle mass.

12.To test your metabolism. Is this possible?

Yes, you can, but not in all countries. The two most common tests are the basic metabolic panel (BMP) and the comprehensive metabolic panel (CMP). Several other types of blood tests and urine tests can assess many metabolic issues, as well.

13.As promised, some examples of non-metabolic diseases.

Metabolism plays a critical role in many bodily functions. Nevertheless, health problems can arise from a variety of other systems and factors. Here are some common categories of health problems that are not primarily metabolic in nature. At times there is overlap.

  • Infections caused by bacteria, viruses, fungi, or parasites can lead to diseases like influenza, pneumonia, tuberculosis, and HIV/AIDS. These conditions are not primarily related to metabolic processes but rather to the body’s immune response and pathogen interaction.
  • Conditions affecting the heart and blood vessels may arise from lifestyle factors. Such conditions include hypertension (high blood pressure), coronary artery disease, heart attacks, and strokes. Lifestyle choices can lead to these issues. Genetics and other non-metabolic factors also play a role.
  • Problems such as arthritis, osteoporosis, and injuries (e.g., fractures, sprains) are related to the musculoskeletal system and mechanical issues rather than metabolic dysfunction.
  • Conditions affecting the nervous system include epilepsy, multiple sclerosis, Parkinson’s disease, and Alzheimer’s disease. These conditions involve neurological pathways and brain function. They are not primarily metabolic in nature.
  • Diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung infections do not originate from metabolic processes. However, they influence respiratory function.
  • Conditions like gastritis, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and gallstones affect the digestive system. These conditions do not necessarily qualify as metabolic diseases.
  • Mental health issues such as depression, anxiety disorders, schizophrenia, and bipolar disorder often have complex causes. These may include genetic, environmental, and psychological factors. They are not purely metabolic.
  • Diseases where the immune system attacks the body’s own tissues are not primarily metabolic problems. Examples include rheumatoid arthritis, lupus, and multiple sclerosis.

I hope you find this text useful. It helped me a lot to better understand the concept of metabolism. Now time for a long beach walk.

Take care and live a happy and healthy life!

Robert, your health friend

(2017) somewhere in Uzbekistan, in need of losing some kilos

28. ARTIFICIAL INTELLIGENCE (AI): YOU AIN’T SEEN NOTHING YET (health project99+)

Beach in South Africa

hapterDear reader,

The integration of artificial intelligence (AI) and quantum technology will dramatically advance the medical sector. This will lead to unimaginable breakthroughs in drug discovery, personalized medicine, and optimized patient care.  Precision treatments, enhanced diagnostic capabilities offer us exciting roads for a longer life as well. 

Old linear models of progress in medicine and longevity will no longer be appropriate.

 Our traditional backward-looking view of history suggests that the future twenty years of advances will be similar to the past. This perspective ignores the exponential nature of what is going on. AI transformation goes beyond adopting new tools; it involves rethinking the fundamentals of how health is delivered and accessed.

Potential for longevity enhancements is one thing. However, it is also crucial to acknowledge the legal challenges. Traditions and ethical considerations slow down these technological advancements. There is a high probability that rapid health advances will remain reserved for a small group of wealthy people. This situation is expected, at least in the initial phase.

1.The place of AI in health- and lifespan

I realize the risk that I oversimplify the complex health dynamics in my text below. Factors such as genetics, environment, and socio-economic status play important roles in health outcomes. Still I like to make the point that healthy lifestyle choices are a determining contribution to better health. 

So painting with broad strikes, most individual lives look as follows. When engaging in harmful behaviors, like smoking, your health span will be about 60 – 65 years. Avoiding the five key areas also contributes to this shortened health span. These areas include food/drinks, exercise, stress/sleep, environment, and social life. The remaining years from 65 to 85 will be spent with an increasing amount of health problems. This sounds bleak, but reality for most.

To improve your health span, the recipe is quite easy. Stop the bad things! Pay attention to the good things. And have some luck of course, but your destiny is in your hands for 80 – 90%.

As I have written before, a first area where there is interesting potential to prolong life is with certain supplements. To name a few: Berberine, Spermidine, Fisetin. For all three there are serious indications that they can contribute to a longer life (longevity).

The integration of AI into drug discovery processes has shown promise in identifying novel compounds. These compounds specifically target the biological mechanisms of aging. This integration improves the efficiency and accuracy of developing longevity-promoting therapies, including supplements.

However, there is much more to AI, including the promise of adding decades to your life. Or even eternal life?

2.AI and longevity in the coming years

Based on all what I read, I am convinced that this decade will feature increasingly dramatic pharmaceutical discoveries. Nutritional discoveries will also increase, largely driven by advanced AI. By around 2030, perhaps the most diligent and informed people will reach “longevity escape velocity.” This is a crucial moment. We can add more than a year to our remaining life expectancy each calendar year that passes. Whether this would be a process without end is too early to tell. However, pushing the end of life somewhere in the 99+ would already be great. 

But let me add that “longevity escape velocity” remains a theoretical concept and hasn’t been substantiated with concrete evidence.

3.AI and longevity in the wild 30’s

For the next decade a bold prediction. Nanorobots are on their way. They will be programmed to destroy all types of pathogens. They will also be able to treat metabolic diseases. Our major internal organs (except heart and brain) put substances into the bloodstream, or they remove them. Many diseases are caused by their malfunction. As we know diabetis type 1 is caused by failure of the pancreatic islet cells to produce insulin.

The future medical nanorobots will monitor the blood supply. They will increase or decrease various substances, including hormones, nutrients, oxygen, carbon dioxide, and toxins. This process will augment or even replace the function of the organs. Using these technologies, in some optimistic scenarios, we will largely be able to overcome diseases. We may also conquer the aging process by the end of the 30’s.  

We will see; many see the paragraph above as overly optimistic or speculative. While advances are being made, completely overcoming diseases and the aging process presents extraordinary scientific challenges. There are also ethical challenges that may not be resolved by the end of this decade.

4.First examples of AI in practice in the early 20’s

AI and computational tools are increasingly employed to facilitate various aspects of vaccine development. These tools are used in the analysis of viral genetic sequences (ref COVID vaccines). This is a work in progress, as is the case everywhere with AI. Results depend on context. They also rely on the quality of the training data and specific algorithms.

AI algorithms are used to analyze medical images, such as X-rays, MRIs, and CT scans. Deep learning models can already detect conditions like tumors or fractures. Their accuracy is comparable to or exceeding that of radiologists. A UK study showed that new AI software is twice as accurate as professionals. It excels at examining the brain scans of stroke patients. 

AI-powered tools are being developed to assist in diagnosing diseases. These tools analyze lab results, patient history, and symptoms to suggest possible diagnoses.

AI is utilized to analyze genetic information and other patient data to personalized medicines. We will see this in the coming few years. 

AI accelerates the drug discovery process by predicting how different compounds will behave in the body. It has access to the 1000’s studies worldwide, something no scientist will ever have.

AI algorithms are used to predict patient outcomes, readmission rates, and disease outbreaks.

Remote Monitoring is on a rapid rise. AI is used with wearable technologies. These technologies monitor patients’ vital signs and health metrics in real-time. 

AI will assist in identifying suitable candidates for clinical trials. It will help predict the spread of infectious diseases. AI will streamline administrative tasks in healthcare settings. Through Chatbots and virtual health assistants, it will provide patients with information, triage symptoms, and remind them to take medications. 

5.Main challenges

Healthcare is “below average” in its adoption of AI, according to a recent World Economic Forum white paper. This is in comparison to other industries.

Adoption will be hindered by three main elements. These are not sexy, but extremely important. First, there is a need for new regulatory complexities. These must align with the rapid adoption of digital health technology. One has to fear that politics in most western countries will not be capable of adapting. There is a reason why Gulf States have the ambition to play a leading role

In the second place the current change management models are outdated and inflexible. In the third place the medical sector (with all respect) is traditionalist and not quick to embrace change.    

Whatever change there will be, we will have to accept that a fundamental rethinking will not occur universally. Many healthcare systems resist change due to entrenched practices. Bureaucratic structures may slow the adoption of AI technologies.

6.Ethical concerns

Some have a strong ethical concern about equity and inequality. A common concern is that only the wealthy will be capable of affording the technologies of radical life extension. In the first phase, this will be the case. Nevertheless, when costs go down, new longevity steps will become available to more and more people. Just look at the history of the cell phone. First a toy and instrument for the wealthy, now there are billions around.

Living for ever is of course even beyond science fiction. Still, in AI circles, you already have ethical discussions about this topic. Not for this blog this time. Current understanding of biology asserts that there is no scientific roadmap that suggests immortality can be achieved. Extending by decades or more however seems increasingly in the realm of the possible.

On this optimistic note,

I remain, Robert, your health friend

Tafelberg, Cape Town

0. MY HEALTH ESSENTIALS: SHOULD IT INCLUDE VIBRATION/WHOLE BODY VIBRATION DEVICES? (health project99+)

Humboldt hotel in Avila/Venezuela

Dear reader,

This blog discusses once-hyped fitness equipment, the Power Plate, and other whole-body vibration devices. I remember its commercial introduction in the early 2000’s, when the famous Dutch soccer player Johan Cruyff endorsed it. As a loyal Dutch soccer fan, I was persuaded to buy one, already 15 years ago.

While the hype has diminished, this vibration technology remains popular, and most fitness centers have one. Does it work? To a certain extent, yes. Do I recommend it? No. Am I against it? No, but there are several health risks linked to its use. My suggestion is to join a reputable gym that offers professional vibration equipment. I wouldn’t pay over 2000 euros to buy a Power Plate for home use again. I completely agree with what fitness professionals say on this topic.

1.What do fitness professionals say?

In summary, there are proven benefits linked to Power Plate. However, opinions on the efficacy of whole-body vibration technology (WBV) differ. Many fitness professionals advocate that WBV should complement, rather than replace, traditional exercise techniques for optimal results. They do find that strength training becomes easier as you incorporate WBV into your routine.

At my gym, we have several workout plans for its very professional whole body vibration equipment. These include strength training, anti-cellulite routines, and fat-burning programs. I also notice that very few people use it.

2.My experience, positive and negative

Positive At home I the power plate for use a few exercises, mainly squats and reinforcing my lower legs. I also do some weights while on the power plate. I love my power plate best when I have an injury with my legs. I lie on my back and place my legs on the power plate. I let the vibration do its healing work. For me it functions and I notice the difference.

Negative See the health risks below. I know it is standard practice to put a disclaimer for every health claim. But, for whole body vibration devices, it is really necessary. In my case from headaches to release of kidney stones.

3.What is a whole-body vibration device/the technique?

The Power Plate is a type of vibration exercise machine. The concept of whole-body vibration training has its roots in earlier research. The Power Plate utilizes this concept. These devices were developed in the 1960s and 1970s.

Whole-body vibration (WBV) involves applying mechanical oscillations to the body. This occurs through a vibrating platform generating vertical and/or horizontal vibrations. This mechanical stimulation activates muscle contractions via the reflex arc, engaging both the somatic nervous system and the neuromuscular system. The vibrations induce a series of rapid muscle contractions, known as tonic vibration reflex. This reflex can enhance muscular strength. It can also improve your body’s ability to sense movement, action, and location and stimulate blood flow. 

Research is ongoing. Indications are that WBV can also influence various physiological responses. These include alterations in hormone levels, increased flexibility, and potential benefits for bone mineral density through) is any of various mechanisms by which cells convert mechanical stimulus into electrochemical activity. These effects occur because kinetic energy from the platform transfers to the body. This transfer impacts both the musculoskeletal and cardiovascular systems. Safety considerations are crucial. It’s important to adhere to recommended exposure guidelines. These measures are essential to mitigate potential adverse effects associated with excessive vibration exposure.

4.(Potential) benefits of WBV-training

Whole-body vibration (WBV) training is exemplified by devices like the Power Plate. Studies have shown its promising benefits. It is effective in enhancing muscle activation and improving bone mineral density. It also supports balance and stability. These factors are critical for maintaining independence and quality of life in older adults. Research indicates that WBV can aid fat cell breakdown. It boosts collagen production and improves circulation. These effects collectively contribute to skin firmness, reduced water retention, and relaxation. Furthermore, WBV may engage in significant recovery support post-exercise by promoting blood flow and enhancing flexibility.

Additionally, there is emerging evidence suggesting that WBV could have anti-aging effects, particularly for older populations. While “anti-aging” can be a broad concept, scientific studies have focused on tangible aspects of aging. These include maintaining muscle strength and metabolic health. They play vital roles in overall health as one ages. By incorporating WBV training into fitness regimens, individuals may derive notable physiological benefits that align with healthier aging. It is often recommended to use it as a complementary tool alongside traditional exercise methods for optimal results.

5.Price/unexplainable differences

Some health essentials are inexpensive, while others are not. The price difference among Power Plates and similar vibration training devices is quite striking. It can range from a few hundred euros to 20,000 euros. Some devices cost merely a few hundred euros. Others can reach up to 20,000 euros. This is approximately 23,000 USD. Despite various comparative studies, I still find it difficult to understand why the price difference can be that huge. One reads also rather favorable research on low-cost models.. While a sturdy, high-end model is essential for a fitness school, is it really necessary for home use? 

The reasons given for the price disparity do not convince me. Factors mentioned include construction quality and advanced vibration technology. This technology allows for more precise control over frequency and amplitude. Additionally, there are more powerful motors that enhance performance and longevity. Additionally, commercial-grade machines are designed for gyms and fitness centers, while lower-cost models are often more compact, targeting home users. Higher-priced models also offer extra features, like programmable settings, larger platforms, and built-in health assessments.

6.Health risks, quite a few

Sessions on vibration plates have general guidelines. Each session should be limited to a limit of 30 minutes. It is preferable to leave two days between sessions. Overdoing it may strain joints, retinas, and organs, which is a worrying thought—especially when you consider the phrase “straining organs.”

The potential side effects of excessive use include headaches and neck pain. They also encompass dizziness, motion sickness, and digestive problems. I have experienced all of these firsthand. Not always, but at times. 

Extra risks mentioned include back pain, nervous system damage, and cardiovascular disease. There is a long list of individuals who should avoid using vibration plates. At the very least, they should consult their doctor beforehand. This list includes pregnant individuals. It also includes those with a history of stroke, heart disease, or diabetes. Individuals with blood clotting disorders, pacemakers, seizure disorders, and ocular disorders are also on the list. 

On a personal note, I would add that those prone to kidney issues should exercise caution as well. I am prone to small kidney stones. After a session on a vibration plate, I have noticed that my stones can become mobilized in my body.

7.Lose weight/burn fat

One of the main claims of the Power Plate is weight loss, but I have my doubts. It might be part of an overall strategy. However, doing exercises on the Power Plate alone won’t be effective. I’ve come across numerous user comments online that confirm the Power Plate alone will not help with weight loss.

In the best case, using the vibration equipment in a fat-burning program may not help you lose weight. The scale might not show fewer pounds. However, you will notice a tighter physique. Fat tissue is often replaced with muscle.

One day, I will write about weight loss. My theory is to set the bar low. Aim for a weight loss of 1 kg per month. Eat less and healthier. Exercise more. This approach works for everyone—believe me.

Now, I’m off to the gym. I’ll spend about 10 minutes on the impressive WBV equipment. Then, I will do some other exercises for the rest of my workout.

Take care and enjoy life!

Robert, your health friend

20. A PLASTIC TSUNAMI ENTERING HUMAN BODIES

Courtesy Greenpeace, plastic in Kinshasa

Dear reader,

Summary: We consume more plastics than we think. Especially the smallest particles, the Nanoplastics, can have a bad effect on your long-term health. Science is working hard, much is still unclear, but signs are not good. Try to limit your contact with plastic significantly. Avoid using plastic bottles, plastic coffee and tea cups and chewing gum. See point 8 how to minimise your exposure to these plastic particles.

  1. Research only at its infancy/I am worried

I know research is ongoing and final conclusions will take years, but doesn’t this micro and nanoplastic stuff sound scary? Plastics might sound innocuous, but there are many types, some of which can cause cancer or other diseases. 

The effect of all these micro- and Nanoplastics entering our bodies is still unknown. The more I read, the more concerned I become. Plastics are a holistic concept, but when you break them down you enter a world dangerous additives. You also read about Nanoplastics as molecular pollutants that attach to fungus, algae and bacteria.

Writing this blog did not help, nor did these alarming headlines: “0.5% of the brain consists of Nanoplastics,” “Nanoplastics found in penises,” and “Nanoplastics entering individual cell structures.”

2, Most experts downplay the risk,

Experts claim that the public is overreacting. A quarter of the Dutch population believes that microplastics, and especially Nanoplastics, are among the top dangers to one’s health. The Dutch are perhaps exaggerating, but probably not. From what I have read this plastic future does not look all too good.

We do not know what interaction might occur between these smallest particles and living organisms. The idea that the tiniest particles can enter your individual cells is worrying. In reality, they do enter your cells. The increasing amount of plastic found in people’s brains is also not a good sign.

Dear reader, I don’t know about you. I am truly concerned. There seems to be no end to the plastic tsunami that overwhelms us. This news from the Netherlands is a bit off topic but related. It states that eggs from free-ranging chickens are too dangerous to eat. Can you imagine? Apparently, there is so much poison in the Dutch soil that it impacts the quality of food the chicken eat. This, in turn, affects the quality of the eggs.

There are actions we can take, such as avoiding these contaminated eggs. Or, in the case of plastics, minimizing their use as much as possible. Below are some tips in this blog.

For everything else, we must keep an eye on scientific developments.

3. Ok, what are micro plastics and Nanoplastics?

Microplastics are small plastic particles. They are usually defined as being less than 5 millimeters in size. However, they can be much smaller. They originate from the breakdown of larger plastic debris, like bottles and bags. They also include fragments of stabilizers, lubricants, fillers, and plasticizes. Manufacturers use these and other chemicals to impart desirable properties to plastics. Such properties include transparency, flexibility, and durability. Many of these chemicals have been classified by experts as toxic and harmful to human health.

Microplastics are widespread in the environment, found in oceans, waterways, soil, and even in the air. They pose increasing environmental challenges. Microplastics contaminate ecosystems and enter food chains, such as in fish. Animals and humans can ingest them, potentially causing harm over time.

Nanoplastics (sometimes calles nanoparticles, but this is a wider concept) are particles less than 100 nanometers in size. This size is less than 1/10,000 of a millimeter. They are much smaller than microplastics and more concerning because they can overcome certain barriers and enter human cells. They can be purposefully engineered in various scientific and industrial processes. For example, they are used for materials like carbon nanotubes. Alternatively, they may occur naturally in some processes. They can also result from the further breakdown of microplastics.

4. Just some plastic statistics

In 2020, approximately 367 million tons of plastics were produced worldwide. This amount is almost double that of 2000, which had an annual production of 200 million tons. Production is still growing on an annual basis.

Researchers estimate that the average person consumes between 78,000 and 211,000 microplastic particles every year. Plastic-based bottled water has a big role in these figures. Hot drinks in plastic cups can also contribute significantly. Together, they can make up to 50% of the intake. And remember, we talk about the micro plastics, the “big” particles, up to half a centimeter! every year through drinking water, foods contaminated by microplastics, and breathing microplastics-containing air. The number of Nanoplastics is infinitively more and can be 200.000 in one plastic bottle with water.

Fortunately, most, but not all leaves our body again the natural way.

In early 2024, a new study revealed that human brain samples collected at autopsy contained significantly more plastic. They had seven to 30 times more plastic than the kidneys and liver. Compared to 2016, this concentration represents about a 50% increase, indicating that, as of today, about 99.5% of the brain is brain tissue and the rest is plastic.

5. Not only plastic bottles and plastic coffee cups are of concern. Chewing gum as well.

A pilot study presented at the American Chemical Society’s spring 2025 meeting revealed that chewing gum can release hundreds to thousands of micro and nano plastic particles into saliva, which are then potentially ingested.

6. Dangers of micro- and nanoplastics

Microplastics and Nanoplastics have infiltrated ecosystems worldwide and have been detected in air, water and soil. Their small size allows them to enter the human body through ingestion, inhalation and dermal contact. Chemical additives like polychlorinated biphenyls and phthalate esters are added to microplastics during production. These additives typically exacerbate health effects. Microplastics are therefore recognized as an emerging environmental concern. They are also a public health concern. These concerns have the potential to affect both human well-being and the natural environment.

The much smaller parts, the Nanoplastics, can penetrate biological barriers. They enter cells and tissues, raising concerns about long-term health effects. It alarms me to learn that microplastic and nano plastic concentrations in brain samples are seven to 30 times higher. These concentrations are notably higher than those in kidneys and liver. As always with relative new developments, more studies need to be done to understand what the health implications are.

The mechanisms by which Nanoplastics enter the brain remain unclear. One hypothesis is that they travel with lipids ingested through food. Human brains are particularly rich in fat, which may help plastics cross the blood-brain barrier. Inhalation of airborne microplastics and ingestion through diet are considered primary routes of exposure.

7. Just one example how plastic pollution originates and affects us all

Biosolids, which are the treated water sludge generated from wastewater treatment, significantly contribute to plastic pollution in terrestrial environments. They are commonly utilized as fertilizers in agricultural land. This practice results in a considerable deposition of microplastics onto farmlands. In Europe, estimates vary between 63,000 to 430,000 tons of microplastics are deposited annually. In North America, the range is 44,000 to 300,000 tons. Consequently, agricultural soils serve as extensive reservoirs of microplastics. These particles are transported to the aquatic environment through various means. These means include rainfall, leaching, and irrigation.

8. First suspected links with diseases

There is ongoing debate over the health impacts of these microplastics within human tissues. These risks encompass inflammation, oxidative stress, and tissue damage. They have been found in vital organs such as the heart, liver, lungs, and even placenta. 

One study also found that individuals with dementia have more plastic fragments in their brains. The amount is three to five times higher than those without the condition. It was noted that dementia can impair the blood-brain barrier and brain clearance mechanisms, possibly creating a “sink” for plastics. Again, no definitive proof yet.

Some experts argue that nano plastics carry harmful chemicals. These chemicals are known to lead to reproductive issues. They cause hormonal imbalances by disrupting the endocrine function.

There appears to be a link between plastics and obesity.

9. What to do?

Summary: reducing exposure to microplastics and nano particles involves several lifestyle and consumer choices. Below some suggestions I summarized from reliable sources on internet.chapter

My own top 5 is: never heat anything in plastic, avoid drinks from plastic bottles (= no 1 tip), do not drink hot drinks from plastic, store in metal or porcelain, repack from plastic in metal, glass or porcelain, not cutting food on plastic cutting-board. I cut everything on an ordinary porcelain plate. And stop chewing gum.

Suggestions from internet

Filtering and boiling water.

Cutting back on plastic use when possible, for example, by using reusable containers

Boosting fiber intake involves two types of fiber. Fermentable fiber found in fruits and vegetables forms a gel-like substance in your gut. This helps trap microplastics and prevents them from entering your system. Meanwhile, non-fermentable fiber helps push these harmful particles through your digestive tract. It does this before they can be absorbed. In a world where microplastics are unavoidable, fiber could be your best defense

Not using single-use plastic over and over.

Avoiding heating plastic food packaging, as plastic particles can spread into the food.

Focusing on good sources for our food is essential. We should ensure our seafood is from sources that have less microplastics, for example.

Avoid foods that are ultra-processed, as there have been some reports of MNPs (=micro and nano plastics) in ultra-processed food.

Wearing natural fiber clothing — organic cotton or hemp — and avoiding those with synthetic fibers.

Vacuuming our homes more often, as microplastics can accumulate in household dust.

Being careful of environmental pollutants as high air pollution areas might have more MNPs in air.

Making sure our environment at home or work has a good air ventilation system.

This was a difficult blog to write. Too little is known about this topic, but from what we know one can only draw one conclusion: stay away as much as possible from plastics, but this will be hard to do.

Robert, your health friend,

traffic in Kinshasa, DRC. On a quiet day

11. SUGAR, THE DEVIL IN DISGUISE/PART 1: SOME BASIC CONCEPTS (health project99+)

Too much sugar is not good for you, but you need some for your energy.” “Sugar is those white blocks you put into your coffee or tea.” “Brown sugar is better than white sugar, but honey is the best.” This is how generations of people viewed sugar, including my parents.

I must admit that I have a sweet tooth. For decades, too much sugar resulted in unnecessary extra kilos for me. My many visits to the dentist testified to the sweets I consumed. I did a lot of sports, which kept things under control and, in general, I followed a healthy diet.

Unfortunately, sugar can be responsible for much more than excess weight or cavities. Before studying health issues, I was unaware of the havoc sugar can wreak on your body, from impacting your brain health to causing fatty liver, similar to the effects of excessive alcohol consumption

While 100% scientific proof is lacking, there are clear indications that sugar is addictive, not unlike hard drugs. To sugar, one should also add nutritionally poor white starch, such as white bread, white rice, etc.

For people with diabetes, spikes in glucose levels are plainly harmful. There is growing evidence of a greater impact from simple carbs. Sugars and refined starches do more than add calories or complicate life for people with diabetes. Added sugars and refined starch can cause health problems that sugars from fruit or complex carbs do not.

Sugar = Carbohydrate

The first thing I learned is that sugar is not a separate food group but a carbohydrate. Realizing that sugar is a carb helped me understand the concept of sugar much better. There are three main groups of carbs (sugar, starch, fiber), with sugars being so-called simple carbohydrates. Their organic formula is a multiple of carbon (C), hydrogen (H), and oxygen (O).

Glucose is a very common sugar. It is a hexose with six carbons (C), twelve hydrogens (H), and six oxygen (O) atoms (C6H12O6). Other common sugars are fructose and galactose (both of which have the same formula), sucrose, and lactose (both C12H22O11).

Sugar is Everywhere

Sugar is ubiquitous in nature. It is present in hundreds of different forms. Examples include lactose in milk or natural sugar in fruits and vegetables. It is the generalized name for sweet, short-chain, soluble carbohydrates, many of which are used in food. They are composed of carbon, hydrogen, and oxygen. Various types of sugar are derived from different sources.

It is also added generously to bread, cereals, pizza, and basically most processed foods. Just read the labels—it will make you depressed to see how high your added sugar intake can be. You also need a scientific degree to uncover the different names for sugar. Generally speaking, chemical names ending in “-ose” indicate sugars. “Syrup” indicates a sugary solution. Malting processes starchy grains like wheat and barley. This method converts them into sugar. As a result, “malt extract” will be mostly sugar.

An Added Sugar Calorie = An Empty Calorie

Your body needs energy (in the form of glucose/ATP). The source of this energy is crucial because you need meaningful calories, not empty calories. Two lumps of sugar give you the same amount of sugar as one banana. However, there is a world of difference. The lump of sugar gives you a fast but short spike in your energy level. In contrast, the sugar in the banana comes with vitamins, minerals, and other important compounds. Not to forget the starch, which can be up to 80% of the weight of unripe bananas. This starch is primarily resistant starch. It improves gut health by acting as a prebiotic. It also helps with blood sugar management. Furthermore, it increases satiety.

Those who think that all calories are the same are wrong. Technically/organically, added sugar is not different from naturally occurring sugars. In other words, sugar in fruit is not healthier than sugar in other products. Your body does not distinguish between naturally occurring sugars and added sugars. However, research has shown that with the empty calories of added sugar, you miss out on all the good stuff. These empty calories increase the likelihood of several diseases, including Alzheimer’s and cancer. A lot of research is ongoing; not all is proven, but there is also a correlation between too much sugar (i.e., easy carbs) and refined starch with certain types of cancer.

Complex Carbs are Better, but Even Here: Moderation is Key

Complex carbohydrates are generally considered healthier than simple sugars. They break down more slowly in the body, providing sustained energy. They are typically accompanied by fiber, vitamins, and minerals. However, consuming them in excessive amounts can lead to similar health issues as consuming sugars and refined starch. However, there are differences in how the body processes complex carbs compared to simple sugars.

What About the Technique of Converting Carbs into Energy?

Foods that contain carbohydrates (sugars, starch) are broken down into glucose in your stomach and intestines. This glucose is then absorbed into your bloodstream and transported to your muscles and organs. It acts as fuel for your body.

Your body uses insulin to help move glucose into your cells, where it is converted into energy. This process is essential for you to think and move. From your brain to your digestive system, all your organs require glucose to function properly.

Sugar = Same Impact on Your Liver as Alcohol (When it is Fructose)

Virtually every cell in the body can use glucose for energy. In contrast, only liver cells break down fructose (=a.o. sugar in fruits and soda). What happens to fructose inside liver cells is complicated. One of the end products is triglycerides, a form of fat. People who consume too much fructose may eventually develop non-alcoholic fatty liver disease. This condition is characterized by excessive fat stored in liver cells.

Experts still have a long way to go. They need to connect the dots between fructose and non-alcoholic fatty liver disease. They also need to make connections with obesity, diabetes, heart disease, and cancer. Higher intakes of fructose are linked to these conditions, but clinical trials have yet to show that it causes them.

Every cell in the body can use glucose. However, the liver is the only organ capable of metabolizing fructose in significant amounts. When people consume a diet high in calories, the liver becomes overloaded. It starts converting the fructose into fat.

Many scientists believe that excess fructose consumption may be a key driver of many of today’s most serious diseases. These include obesity, type II diabetes, heart disease, and even cancer. If you eat a typical Western-style diet with a lot of refined starch, you stress your liver. You end up damaging it in the same way alcohol does. In fact, fructose is virtually identical to alcohol in the metabolic havoc it wreaks.

Fruit is Much More Than Fructose

Stick with fresh fruits, especially berries, to maintain a healthy level of fructose intake. Avoid fruit juices, sodas, and other sweetened products. You would need to consume a significant amount of fruit. Only then would you come close to the fructose level in a single bottle of soda or fruit juice. More importantly, fruit isn’t just fructose. It’s also a rich source of vitamins, minerals, phytonutrients and fiber – things that make you healthier. 

And what about too much glucose?

Excess glycogen is stored in the liver where it may be used later for energy. Your muscles are also a storage area for glycogen. Excess glucose above this can be converted into triglycerides which are stored in your fat cells. Note that any type of excess calories, no matter which macronutrient they come from can lead to body fat gain. There is nothing inherent in carbs, glucose, or glycogen that increase your risk of gaining body fat.

Carbs as one of the three main groups of macro nutrients

We know that there are three main groups of macronutrients: carbs, protein and fats. In additions there are minerals, flavonoids, vitamins, electrolytes and much more. 

Carbs include sugars in all its forms. They can be divided into three main groups: sugar, starch, and fiber. This is how labels on your food items have divided the carbs.

Some words on the second group of carbs: “starch” (for Dutch readers “zetmeel”)

Whole vs. Refined starch. Starches in whole food forms, such as whole grains, legumes, and vegetables, come with fiber, vitamins, minerals, and phytonutrients. These nutrients make them a healthy part of a balanced diet. Refined forms (white bread, white rice, white pasta etc) are stripped of these nutrients during processing. As a result, they can lead to rapid spikes in blood sugar. They are not much different from added sugar in their negative health effect.

A note in between about phytonutrients

Phytonutrients, also known as phytochemicals, are naturally occurring compounds found in plants. They are believed to provide health benefits beyond basic nutrition. These compounds are not essential nutrients in the traditional sense. They are not required by the human body to sustain life like vitamins or minerals are. However, they are thought to support health and may help reduce the risk of certain diseases.

Most diets are based on 50% intake of carbs.

Most nutritionists advice to eat 50% of your calories as carbs, 25% protein and 25% fats. The only group of macronutrients that can be eliminated is the carbs.  Fats (and as a last matter of resort also proteins) can provide the additional needed energy when taking out carbs. 

That is why there are carbs-poor diets. People who follow these types of diets can reach the stage of ketosis. Severe carb limits can cause your body to break down fat into ketones for energy. This is called ketosis. Ketosis can cause side effects such as bad breath, headache, fatigue and weakness. It’s not clear what possible long-term health risks a low-carb diet may pose.

I have no comments on diets. In practice my carbs intake is below 50% and my fat intake more than 25%. Carbs-poor/free diets work for many. However, one should not forget that good (=complex) carbs offer many specific excellent compounds.

Fiber, the third carb group (in addition to sugars and starch)

Fiber, also known as dietary fiber, is a type of carbohydrate that the body can’t digest. Unlike other carbohydrates, which are broken down into glucose, fiber passes through the digestive system relatively intact. Fiber is primarily found in plant-based foods and is an essential part of a healthy diet.

The recommended daily intake of fiber varies with age, sex, and life stage. Generally, it is suggested that adults consume about 25 – 30 grams of fiber per day. But, most people do not get enough fiber in their diets. Too much is not unhealthy, but can lead to bloating.

Soluble Fiber dissolves in water to form a gel-like substance. It’s found in foods like oats, fruits (e.g., apples, citrus), barley, and legumes. Soluble fiber can help lower blood cholesterol and glucose levels.

Insoluble Fiber does not dissolve in water and helps add bulk to the stool, which aids in regular bowel movements. Foods high in insoluble fiber include whole grains, nuts, beans, and vegetables such as cauliflower, potatoes, and carrots.

This blog for starters, there is much more to tell about sugars!

Take care, live a happy and healthy life,

Robert, your health friend

15. THE GREAT DANGER OF LOSS OF MUSCLE (“SARCOPENIA”): WITH SOME HARD WORK OFTEN REVERSIBLE (health project99+)

Summary. You need to start taking care of your muscles early on. If not, you can begin to lose 3–5% of your muscle mass every 10 years starting at the age of 30. Once you turn 60, this loss can speed up to about 10% per decade. The really good news is that muscle loss, known as sarcopenia, can almost always be reversed to a large extent! Which is a good thing as sarcopenia can be life-threatening.

Does losing muscle matter? Yes, it does so, very much—especially if you want to live a long and healthy life. For me, keeping my muscles strong has become one of the top five things to focus on! I didn’t always know how important strength training was. Lucky for me, I’ve always been active with sports, but I ignored strength and flexibility exercises like yoga. That changed once I learned about the dangers of sarcopenia. Now, I do daily exercises like push-ups, planking, balancing on one leg, and yoga. I also make sure to eat the right foods and take helpful supplements. When I am not in the mood I just take a look at the summary of risks (see point 3).

1. What is in a name?

Different terms like atrophy, myopenia, and sarcopenia are often used. I won’t go into their specific definitions, but they all generally refer to the same thing: loss of muscle. This muscle loss can be caused by illness, accidents, hormonal changes, or genetics. However, in this blog, I focus on the most common type: reduced muscle mass caused by disuse and aging.

Symptoms include a decrease in muscle mass. One limb may be smaller than the other. Legs can become thinner. Sensations like numbness, weakness, and tingling might appear in your limbs.

2. Sarcopenia = global pandemic

Up to 40% of people worldwide suffer from sarcopenia. This condition will affect more people globally. An estimated 22% of the world’s population will be over 60 years old by 2050. Older women are at greater risk of experiencing mobility issues.

3. Summary of risks

Sarcopenia poses several potential dangers and serious challenges, especially for older adults. Here are some of the key risks and issues.

1. Decreased Mobility: loss of muscle strength affects an individual’s ability to carry out daily activities. These activities include walking, climbing stairs, and getting out of a chair. Recovery from injuries will also be slower.

2. Increased Risk of Falls and Fractures: Many of us have heard stories of active 90-year-old people who fall, never fully recover, and pass away within a few months.

3. Metabolic Changes: These changes can contribute to conditions like insulin resistance and type 2 diabetes. Additionally, cardiovascular diseases and osteoporosis may also be of concern.

4. Decreased Physical Resilience: With reduced muscle mass, recovery from illnesses can be slower. Recovery from injuries or surgeries may also take longer. Additionally, the risk of complications may increase.

In short, when you have sarcopenia, you risk entering a self-reinforcing cycle of negative health outcomes. This includes reduced activity and increased weakness. Both are potentially life-threatening.

4. How to fight and prevent sarcopenia? 

A. Strength training, balancing exercises and yoga.

Food, as always, is important, and supplements can have some benefits, but physical activities are most essential. YouTube has great videos on what exercises to do, in addition to regular activities like walking, swimming, and cycling. Key exercises involve resistance training and weightlifting. Sports like yoga help you stay flexible. Or, in my case, they help me finally become flexible. Almost daily, I do 45 minutes of push-ups, planking, weightlifting, and some yoga. Maintaining balance should also be part of this routine, so I perform some exercises daily on one leg. It’s not easy at all.

B. What foods should you eat to avoid sarcopenia?

High-quality diets that are rich in fruits and vegetables are essential. Adequate protein intake, especially high in leucine, is also crucial. Hydration is the cornerstone of nutritional plans to fight sarcopenia. Nothing new, as this is general advice for almost everything health related.

C. Which supplements to take?

1. Reliable internet sources suggest that a daily dose of omega-3 oils may slow the aging process. A fair summary indicates that it may also increase the number of years spent in good health. Suggested quantities to take: 4,200 mg of omega-3s. This includes 2,700 mg of EPA and 1,200 mg of DHA. (Note: all info from the internet).

2. Proteins, particularly those with essential amino acids, are crucial. There are nine amino acids that the body does not produce itself. They are somewhat confusingly referred to as “essential” because they must come from external sources. All nine essential amino acids are important for muscle growth. These amino acids are vital for maintaining our body because they are the building blocks of protein. However, one particular essential amino acid that is often highlighted for its role in muscle protein synthesis is leucine. The quantities to take are explained in my blog on protein (see link), with the main messages being: a) it is not easy to get as much as needed, and b) the older you get, the more you need.https://shakethehealthtree.com/index.php/2025/02/25/5-power-to-the-proteins-and-also-enough-is-not-always-enough/

5. Some more info about Omega-3.

Omega-3″, often also called “omega-3 fatty acids” are a type of polyunsaturated fat (the so called ‘good fat’). These omega-3s play critical roles in maintaining heart health, supporting brain function, and reducing inflammation, among other benefits.

There are several types of Omega-3, with the most important being: EPA (Eicosapentaenoic Acid) – Found mainly in fish and seafood. DHA (Docosahexaenoic Acid) – Also found in fish and seafood and especially important for brain health. ALA (Alpha-linolenic Acid) – Found in plant sources such as flaxseeds, chia seeds, and walnuts.

The body can partially convert ALA into EPA and DHA. However, the conversion rate from ALA to EPA and DHA is very low for humans (5%). You need to eat over ½ kg of walnuts daily to get enough EPA and DHA through walnuts. Not practical. I will write a blog about Omega-3 as a supplement. The main conclusion is that most supplements are not as good as natural Omega-3s.

Time for some exercises. Lead a happy and healthy life.

Robert, your health friend

With our beloved dog Randy

9. FOUR DRINKS: (C) THE EVENING VEGETABLES SOUP (health project99+)

Summary: by turning solid vegetables into soup, for six years I now easily meet my daily vegetables target. And my body is grateful for it.

1. I don’t like vegetables...

I’ve never been a fan of vegetables. I would tolerate only peas and maybe some carrots. They had to be covered in Dutch apple sauce (which is not healthy because of its high sugar content). Potatoes and especially French fries got a pass. They might count as veggies, but peeled and fried, they do not offer much health benefit.

I have known all these years, of course, that vegetables should play a starring role in any healthy diet. My mother said a thing or two about it, if I remember correctly. Willpower is essential for any lifestyle change. The motivation to eat these green, red, orange and white things was just lacking. I will write about the importance of will power (and the lack of it) in another blog.

2. But…….

About six years ago, my wife decided she’d had enough of my veggie aversion. She started making vegetable soup, using fresh or frozen vegetables only. A blend of persuasion and gentle insistence managed to get me to eat it daily. It was a brilliant move and since then, I haven’t looked back. Vegetables are now an integral part of my diet, and the numbers from my annual health tests show the benefits. *(For context, biomarkers are biological molecules that indicate normal or abnormal processes or conditions in the body.)

3. More about vegetables

I enjoy incorporating a variety of vegetables into my meals. I include red beets, broccoli, spinach, carrots, cauliflower, pumpkin, and sweet potatoes. I like to spice things up with a bit of celery or leek—I would use onions, but I’m unfortunately allergic. Instead of combining all these vegetables at once, I prefer selecting a mix that suits my needs. Not always a culinary success, by the way, but that is part of the process. Healthy they always are!

Each vegetable brings its own unique benefits. For example, beets are touted for their potential health properties, including (unproven) anti-cancer claims. Broccoli and spinach offer around 3 grams of protein per 100 grams. Sweet potatoes are particularly impressive, containing 35% fewer carbs than regular potatoes and packed with vitamins and minerals. 

All these vegetables are excellent sources of fiber which is crucial for health. Good to know as it can be challenging to consume fiber in sufficient quantities, just as it is with protein. Life is unfair because if we compare proteins and fiber with sugar, there the opposite is true. Sugar, our common dietary foe is found in many forms in our food and very easy to overeat.

One caveat. Some vegetables have a surprising amount of sugar as well, so be careful. For example, carrots contain 6 grams per 100 grams, beetroot has 8 grams, and pumpkin 5. In contrast, broccoli contains only about 0.4 grams.

4. At home we have a diet that is 3/4 liquid

A. Lemon juice to start the day and as a drink in between (1 liter). https://shakethehealthtree.com/index.php/2025/02/25/5-lemons-and-limes-health-project-99/

B. A large smoothie for breakfast and lunch (up to one liter). I already wrote about this morning routine.  https://shakethehealthtree.com/index.php/2025/03/10/9-four-drinks-a-morning-afternoon-smoothie-health-project-99/

C. A fresh soup for the evening, with some carbs and proteins like fish, 0.4 liters. 

D. Two glasses of water/lemon juice with collagen and creatine (0.5 liters), one in the morning with added protein, and one in the evening without extra protein. 

5. Carbs, meat, fish

We aren’t against carbs. They just need to come in the form of whole food. We prefer these over white bread, white rice, or light pasta. We don’t eat much meat, and when we do, it’s mainly organic chicken. We consume fish more frequently, though less than before due to a variety of increasing concerns ranging from mercury to nano-plastics. And I already wrote about the (too) big role nuts play in my diet.

6. Preparation

I mostly use frozen vegetables for their health benefits, cleanliness, practicality, and affordability. When I buy fresh, I cook and freeze them for later use.

I start by boiling approximately ½ kg of frozen vegetables. After boiling for a few minutes, I transfer everything into a blender. I then add salt, pepper, two teaspoons of olive oil, and a generous amount of herbs. Once blended, voilà—a delicious vegetable soup is ready, although not always perfect! Too much cauliflower for example is not to my taste :).

Enjoy a happy, tasty and healthy life,

Robert, your health friend

Cool guys in the DRC, when times were more peaceful

9. FOUR DRINKS: (A) MORNING & AFTERNOON SMOOTHIE (health project 99+)

Summary: smoothies, when well prepared, should be an important part of your daily diet; in mine it is. Be careful with the hidden sugars though, as the negative effect of natural sugar is not different from that of added sugar!

1. Take it easy 

People who write about health might come across as too fanatic. Sometimes they may also seem too principled. To a certain extent I am, but not too much, I hope. At home, we do eat some carbs. I do not mind the occasional croissant (from Lidl — they weigh less than 10 grams, are very fluffy, with hardly any butter, and cost 0.45 euro cents 😊), a sandwich with an egg, some sweet potato French fries, or rice crackers with goat cheese. A few pieces of dark chocolate, normally in the morning, and nuts (sometimes too much) during the day.

2. Not anti, just careful

Solid food-wise, we do not eat meat. We also do not have daily plates with pasta or rice. Nor do we have six sandwiches with the famous Dutch cheese or peanut butter. As I stressed before, my wife and I are not anti-carbs. We are also not anti-meat, and definitely not anti-Dutch cheese. When offered a delicious piece of Pavlova, I will not refuse. However, the emphasis on liquid food serves us well. Without eating less, my weight went down from 96 kg to 82 – 84 kg in one year. We do practice a light form of intermittent fasting (not eating for 12 – 14 hours per day).

More about my eating habits in other blogs, but for now the focus on morning & afternoon smoothie.

3. A “Liquid” Diet with Four Components

However, the main staple of my diet is “liquid”: 

1. A large smoothie for breakfast and lunch (up to one liter). 

2. A fresh soup for the evening (most of the time combined with fish), 0.4 liters. 

3. Lemon juice to start the day and as a drink in between (1 liter). https://shakethehealthtree.com/index.php/2025/02/25/5-lemons-and-limes-health-project-99/

4. Two glasses of water/lemon juice with collagen and creatine (0.5 liters), one in the morning with added protein, and one in the evening without extra protein. 

These quantities are rough indications only.

4. Be careful: risk of sugar overload

Smoothies can be great. They taste delicious. When prepared well, they can offer a load of useful nutrients, proteins, and fiber. However, there’s one risk: too much sugar. Recommended highest quantities of added sugar vary, depending on the country, gender, activity level, etc., ranging from 20 to 50 grams daily. This is not much .

5. Yes, there are differences between added and natural sugar, but…..

You often hear there’s a big difference between added sugars and natural sugars. While it’s true to some extent, natural sugars are part of whole foods and come with all their benefits. However, added sugar is simply sugar. Your body doesn’t distinguish between natural and added sugars. In short, be careful. Do not think that you can eat and drink unlimited amounts of milk, for example, or natural juices. They have natural sugar but they have same negative and highly addictive effects as added sugar. In other blogs, I will focus a lot on sugar.

6. Sugar Examples of popular smoothie input

In my smoothies, bananas contribute the most sugar, up to 15 grams per banana. Berries add about 5 grams per 100 grams, making them a better choice. Avoid milk, as it contains lactose—a form of sugar—beyond its fat content; in stead of milk I use unsweetened soya milk. Mangoes and pineapples, both popular smoothie ingredients, also have high natural sugar content, between 10 – 15 grams per 100 grams.

7. My Experience

In my daily diet, I easily consume half of my allowed sugar intake through smoothies alone. If I’m not careful, I consume even more. Therefore, with natural sugars included, I have about 20 – 25 grams left for the rest of the day. For instance, carrots, which I use in soup, have 5 grams of sugar per 100 grams, and light French quark adds 3-4 grams.

I don’t want to overwhelm you with details. The point is clear: with smoothies and evening soup, it’s easy to reach or exceed the daily sugar limit. This leaves few options for those who have a sweet tooth, perhaps allowing just a cookie or a small piece of apple pie. That’s why my go-to snack are nuts!

Okay, the smoothie as I prepare it (more or less)

  • The liquid base consists of lemon juice (100 ml) and unsweetened soy milk (500 ml). It also includes some water. At times, it contains leftover soup from the evening before.
  • I use banana and berries, or berries and mango, or just berries.
  • I always add one avocado and some broccoli or spinach.
  • In addition to these ingredients, I have a combined protein/collagen drink in the morning and collagen only in the evening (0.5 liter).
  • For additional fiber, I include some fine oatmeal.
  • I add one spoon of chia seeds. Then, I add two spoons of ground flax seeds and some black pepper. This is to enhance the effect of curcumin. I also add a teaspoon of cinnamon.

8. The end result?

Something very healthy, delicious and tasting remarkably sweet.

Enjoy your smoothie, enjoy your life,

Robert, your health friend

Central Park, New York City

2. FROZEN OR FRESH VEGETABLES AND FRUIT? PARENTS ARE NOT ALWAYS RIGHT (health project 99+)

Our parents, at least mine, believed wholeheartedly that fresh vegetables and fruits are “better” than frozen. Sorry, Mom and Dad, but you weren’t correct, at least not for 90%. For most vegetables and fruits, my motto is: buy them frozen or freeze them if you buy large amounts of fresh produce. A few points I give my parents: freezing lettuce is a remarkably bad idea. Bananas should be eaten fresh from the peel, so to speak, and only frozen if you’re using them for smoothies.

I will dive into the differences between fresh and frozen. Let me make one thing clear: both are good choices. They are necessary as part of a healthy lifestyle.

1. Let us define “better.”

a. Nutritional Value: Frozen vegetables are often frozen shortly after harvest, preserving many nutrients and vitamins. Fresh vegetables might take some time to get from the farm to your table. During this period, some nutrients might degrade. This is especially true if they are improperly stored for prolonged periods. Point for frozen.

b. Availability and Cost: Frozen vegetables can be a practical choice when certain fresh vegetables are out of season. Additionally, frozen vegetables are often less expensive than fresh ones. They also have the advantage of a much longer shelf life without losing quality. This is a very important point. A family of four can easily save over 1000 Euros per year. This can be achieved by buying frozen vegetables and fruit in bulk during sales. Moreover, by not discarding wilted vegetables, you save a lot as well. You will need a large freezer, preferably a standing one, as they offer the best overview. In my opinion, a freezer is one of the best investments you can make, both health-wise and financially. Point for frozen.

c. Quality and Taste: Fresh vegetables, particularly when in season and locally sourced, can offer better texture and taste. However, frozen vegetables generally retain good flavor, though their texture could differ slightly after cooking. Point for fresh.

d. (Bacterial) Contamination: We should not underestimate the hygienic conditions. There is often a lack of these conditions under which fresh vegetables and fruits are transported and handled. This is especially true beyond professional handling, at the grocery store and in your home. Fresh produce might not be as thoroughly washed as frozen varieties. Hence, it’s advisable to wash fresh vegetables thoroughly before consumption. Point for frozen.

e. Convenience: For the lazy ones among us (like me), frozen vegetables are typically washed, cut, and ready to use. They save time in the kitchen, which can be particularly beneficial for people with busy schedules. Point for frozen.

f. Use of Pesticides: A growing concern for many. As far as I could find, there’s no significant difference between frozen and fresh regarding pesticides. You must assume that frozen food is well washed and consequently has reduced pesticide residue. Yet, washing after thawing can be tricky. Conversely, fresh produce can be washed thoroughly. All in all, this one is a tie.

So, it’s 4-1 for frozen, with 1 tie.

2. My Experience

Most of the vegetables and fruits we buy are frozen, for all of the reasons mentioned above. My wife and I drink our fruit/vegetables smoothies daily. We also consume lemon juice and soup. So, we have a high turnover of fruits and vegetables. We only buy fresh when we’re preparing dinner with friends or when fresh produce is at a very attractive price. In that case, some cooking is involved afterward to prepare for freezing.

Purchasing our beautiful 2-meter-high, deep purple stand-up freezer has proven to be one of our best health (and monetary) investments. It’s always full, including many 1 kg bags purchased at low prices. Being Dutch, I love a good deal.

3. Which Vegetables Can Be Frozen?

Most vegetables can be successfully frozen with minimal quality loss. Here are a few guidelines:

Green beans, broccoli, cauliflower, carrots, and spinach freeze well, especially if blanched before freezing. 

Peppers, peas, and corn also freeze well without much loss in texture and flavor.

4. Less Suitable for Freezing

Potatoes and zucchini can become mushy due to their high water content.

Lettuce and other leafy salad greens aren’t ideal as they become limp upon thawing.

Cucumbers and celery also lose much of their crispness after freezing.

5. Freezing Fruits

Not all fruits freeze equally well, but many can be frozen successfully while maintaining flavor and nutrition. In my experience, a smoothie is the main use of frozen fruit.

6. Suitable for Freezing

Berries like strawberries, blueberries, raspberries, and blackberries freeze well. They are great for smoothies or baking but less suited for eating fresh.

Bananas can be frozen, preferably peeled and sliced, for smoothies or banana bread.

Stone fruits such as peaches, plums, and nectarines freeze well when peeled and sliced.

Pineapples and mangoes also freeze well when cut into pieces.

7. Less Suitable for Freezing

Watermelon and melons generally become mushy when thawed due to high water content.

Apples can soften after thawing; they’re better for cooking or smoothies after freezing.

Pears can also become too soft unless used in cooking or baking after thawing.

8. Some Techniques

It helps to freeze fruit in a single layer on a baking sheet. This should be done before transferring it to airtight bags or containers. Doing this prevents clumping.

Washing and preparing fruit (peeling, pitting, slicing) before freezing is ideal.

Blanching involves briefly immersing vegetables in boiling water, then quickly cooling them in ice water. It deactivates enzymes that cause quality deterioration, preserving color, flavor, and texture.

9. A Few Words on Nitrates

When discussing vegetables, the topic of nitrates often arises, especially in relation to spinach and leafy greens. Each time, I get concerned because excessive nitrates can lead to various diseases, including certain types of cancer. Fortunately, nitrates are not typically harmful. as long as they’re part of a healthy diet, even when they are present in high levels in some vegetables. Risks only arise when there’s an imbalance. This can happen by eating many leafy vegetables in combination with high nitrate consumption from cured or processed meats or contaminated drinking water.

Enjoy a happy, tasty and healthy life,

Robert, your health friend